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Theoretical/Practical Course and Symposium


February 18–28, 2019

Institut Pasteur de Montevideo, Uruguay


Organising Institutions: Universidad de la República, Centro Investigaciones Biomédicas (CEINBIO), Institut Pasteur de Montevideo  

Organisers: Beatríz Alvarez, Marcelo Comini, Gustavo Salinas and Madia Trujillo


Course description

Thiols in proteins and cofactors serve catalytic, structural, metal-binding and regulatory functions and they are key to metabolism, signaling, antioxidant defense and protein folding. The course will provide an integrated and updated view of thiol-dependent redox processes through theoretical lectures, experimental activities, and seminars.

Course and Symposium topics

  • Reactive oxygen and nitrogen species and cysteine oxidation
  • Chemistry of thiols
  • Chemical biology of sulfur metabolism and hydrogen sulfide
  • Selenocysteine and selenoproteins
  • The structural biology of redoxins
  • Disulfide-bond formation and protein folding
  • Thiol-dependent antioxidant systems
  • Alternative thiol-based redox systems
  • Metallo-thiol-based redox switches and biosensors


International invited speakers

Ruma Banerjee, Cristina Furdui, Tobías Dick, Elias Arner, Mehmet Berkmen, Luis Soares-Netto, Javier de los Santos.



Master or Doctoral students in Biology, Chemistry, Biochemistry, Biotechnology, Bioinformatics, Medicine and related areas. Currently working, or with the prospect to work in the near future, in subjects linked to the course. Applicants to the course should send Curriculum Vitae, a motivation letter and a letter of recommendation from the tutor(s).


Important deadlines and info:

ICGEB grants are available for students and young researchers, covering registration fees for Symposium, meals (lunchs, coffee breaks and opening and closing reception), lodging and shuttle bus to/from meeting venue.

ICGEB-deadline for fellowship applications: December 2nd 2018.

Click here for application form

For technical inquiries, contact thiols2019@gmail.com