Otto Pritsch

Otto Pritsch 2019-01-28T13:08:22+00:00
PhD Otto Pritsch
PhD Otto PritschAssociate professor at the Immunobiology Departament, Faculty of Medicine, Udelar

IMMUNOVIROLOGY LAB

  • Magister in Biological Sciences (Biochemical option). PEDECIBA-Faculty of Sciences- Universidad de la República (1992)

  • PhD in Fundamental Immunology. Diderot University Paris 7 – Pasteur Institute of Paris (1997)

  • Molecular Immunology

  • Molecular Virology

  • Molecular interactions

  • Immunotechnology

  • Protein biophysics

  • Conformational plasticity of the native retroviral capsid revealed by X ray crystallography. Obal G, Trajtenberg F, Carrión F, Tomé L, Larrieux N, Zhang X, Pritsch O, Buschiazzo A. Science 349(6243):95-98, 2015

  • Search for an aetiological virus candidate in chronic lymphocytic leukaemia by extensive transcriptome analysis. Rego N, Bianchi S, Moreno P, Persson H, Kvist A, Pena A, Oppezzo P, Naya H, Rovira C, Dighiero G, Pritsch O. British Journal of Haematology 157(6):709-17, 2012.

  • Immunoglobulin heavy chain V-D-J gene rearrangement and mutational status in Uruguayan patients with chronic lymphocytic leukemia. Bianchi S, Moreno P, Landoni AI, Naya H, Oppezzo P, Dighiero G, Gabús R, Pritsch O. Leukemia & Lymphoma 51 (11): 2070-2078, 2010.

  • Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes. Moratorio G, Obal G, Dubra A, Correa A, Bianchi S, Buschiazzo A, Cristina J, Pritsch O. Archives of Virology 155(4):481-9. 2010.

  • Post-transcriptional regulation of Inducible Nitric Oxide Synthase in Chronic Lymphocytic Leukemia B cells in pro-apoptotic and anti-apoptotic culture conditions. Tiscornia, A.; Cayota, A.; Landoni A.I.; Brito, C.;Oppezzo, P.; Vuillier, F.; Robello, C.; Dighiero, G.; Gabús, R.; Pritsch, O. Leukemia 18: 48-56, 2004

  • Production and functional characterization of two mouse/human chimeric antibodies with specificity for the tumor-associated Tn antigen. Oppezzo, P.; Osinaga, E.; Tello, D.; Bay, S.; Cantacuzene, D.; Irigoín, F.; Ferreira, A.; Cayota, A.; Alzari, P. and Pritsch, O. Hybridoma, 19: 229-240, 2000.

  • Expression of Unmutated VH Genes is a Detrimental Prognostic Factor in Chronic Lymphocytic Leukemia. Maloum, K.; Pritsch, O.; Magnac, C.; Vuillier, F.; Davi, F.; Troussard, X.; Mauro, F.R.; Bénichou, J.; Merle-Béral, H. and Dighiero, G. Blood, 96: 377-379, 2000.

  • Can Immunoglobulin CH1 constant region domain modulate antigen binding affinity of antibodies? Pritsch, O.; Hudry-Clergeon, G.; Buckle, M.; Pétillot, Y.; Bouvet, J.P.; Gagnon, J.; Dighiero, G. Journal of Clinical Investigation 98, 2235-2243, 1996.