The Molecular, Cellular and Animal Technology Program (ProTeMCA) has as mission to integrate the knowledge and technological capabilities of different groups of the Institut Pasteur of Montevideo to promote the development of research and innovative technology in the area of genetic engineering, bioassays and models based in proteins, cells or animals.

Stressing the link of scientific knowledge with its application, through dynamic interaction with academia and industry, the program seeks to contribute to solve problems in biotechnology using new tools, products, processes or services. It also collaborates with research groups or private institutions to develop molecular technologies that help the improvement of (bio) drugs, cells or animals.

Within the IP Montevideo, the program involves the joint work of the Cell Biology Unit, the Redox Biology of Trypanosomatids Lab, the Transgenic and Experimental Animal Unit and the Biomolecular Simulation Lab.

Ing. Biotec. Karin Grunberg
Cell Biology Unit
Dra. Cecilia Abreu

Founding Members

Dra. Mariela Bollati
Cell Biology Unit
Dr. Marcelo Comini
Redox Biology of Trypanosomatids Lab
Dra. Martina Crispo
Transgenic and Experimental Animal Unit, UATE
Dr. Sergio Pantano
Biomolecular Simulation Lab
  • Design and refinement of products of biotechnological interest

  • Development of new high performance cellular assays

  • Cell or animal models for toxicological studies and diseases

  • “XTREME- Bruker in vivo imaging technology”. February 2017, Montevideo.

  • “ICGEB Course: Cell and animal models for drug discovery”.October 2017, Montevideo.

  • “Alternatives methods to animal research”. May 2018, Montevideo.

  • 2019-2021 – New molecular tools for the reduction of production costs of bioactive molecules (FMV_3_2018 _l_148443, ANII). Responsible: Cecilia Abreu.

  • 2016-2019 – Design and production of new variants of the follicle stimulating hormone (FSH) for its use in species of productive interest – National Agency for Research and Innovation, ANII (ALI_1_2015_1_5084). Principal Investigator: Mariela Bollati-Fogolin.

  • 2015-2018 – Design of biosensors for simultaneous monitoring of redox signaling and cAMP: from the computer to the cell and back to the computer – National Agency for Research and Innovation, Project FMV_1_2014_1_104000. Principal Investigator: Sergio Pantano.

  • Piattoni CV, Sardi F, Klein F, Pantano S, Bollati-Fogolin M, Comini M. New red-shifted fluorescent biosensor for monitoring intracellular redox changes. Free Radic Biol Med. 2019 Feb 5;134:545-554