Escuela de Cristalografía de Macromoléculas : Biología Estructural para una investigación con impacto en biomedicina

>>>Escuela de Cristalografía de Macromoléculas : Biología Estructural para una investigación con impacto en biomedicina

Institut Pasteur de Montevideo

Montevideo, Uruguay


This Workshop is in continuity with several previous editions, which have taken place in Montevideo (Uruguay) and São Carlos (Brazil) since 2010. This joint effort between CeBEM and CCP4 has become a regional School of Structural Biology, aimed at covering all aspects of the macromolecular structure determination process using X ray crystallography: starting from data processing, through phasing and refinement to structure completion and analysis. Gradually, integrative methods are also being included. In particular, this year an introduction to cryo-electron microscopy has been added to the program. The full program of activities will shortly be available within this site.

The workshop will cover many popular programs used for data processing and structure determination, with the developers available to help throughout the meeting. Programs covered will include: Mosflm, Scala, XDS, Autoproc, Buster, Refmac, ARP/wARP, Phaser, AutoSharp, Arcimboldo, Coot, SHELXC/D/E, BALBES, MrBUMP, Crank, Buccaneer, CCPEM and many more.


  • Alejandro Buschiazzo, PhD. Institut Pasteur de Montevideo, Uruguay
  • Ronan Keegan, PhD. CCP4, STFC Rutherford Appleton Laboratory, United Kingdom
  • Richard Garratt, PhD. Instituto de Fisica de São Carlos, Brazil


  • Alejandro Buschiazzo, Montevideo, Uruguay
  • Grzegorz Chojnowski, Hamburg, Germany
  • Paul Emsley, Cambridge, UK
  • Richard Garrat, São Carlos, Brazil
  • James Holton, San Francisco/Berkeley/Palo Alto, USA
  • Ronan Keegan, Oxford, UK
  • Eugene Krissinel, Oxford, UK
  • Andrey Lebedev, Oxford, UK
  • Andrew Leslie, Cambridge, UK
  • Garib Murshudov, Cambridge, UK
  • Colin Palmer, Oxford, UK
  • Raj Pannu (TBC), Leiden, Netherlands
  • James Parkhurst, Oxford, UK
  • Randy Read, Cambridge, UK
  • Clemens Vonrhein, Cambridge, UK
  • Isabel Usón, Barcelona, Spain

The preliminary program is available here


People interested in participating in this course must fill out and send the Application Form, together with the following documents:

  • short CV (max. 3 pages)
  • letter of support from your laboratory Head

Applications should be sent to:

A maximum of 24 students will be accepted.

Deadline for applications : September 17th, 2017.

The registration fees are covered by the Workshop.

Support for accommodation, per diem and local transportation will be provided to all participants from abroad.

Supported by: Collaborative Computational Project Nº4 (CCP4, UK) & Science and Technology Facilities Council (UK), Centro de Biologia Estructural del Mercosur (CeBEM), International Union of Crystallography (IUCr), and Institut Pasteur de Montevideo.

For further information please contact:


The course is intended mainly for graduate students, postdoctoral researchers and young scientists in the area of structural biology. Candidates working in South American countries will be prioritized, but applications are welcome from all around the globe. The school is not meant as an introductory level course to protein crystallography. For those that wish to catch up with required introductory concepts, a first day will be optional, dedicated to an overall view of important theoretical concepts. Applicants with reasonable expertise in crystallography and some experience with the CCP4 suite will definitely make the most out of the Workshop.

The purpose of the school is to address specific problems that the applicants face while processing diffraction data and while solving and refining novel structures. Applicants with collected data or partially processed data will be given strong consideration, particularly if they are having trouble with image processing, phasing or refinement. However, these are not mandatory requirements and all applications will be considered.

Several of the leading PX software developers from around the world will present lectures and tutorials on their software, and will also be available to help with problems during hands-on sessions throughout the workshop.