Otto Pritsch 2018-10-09T12:44:50+00:00
PhD Otto Pritsch
PhD Otto Pritsch

Laboratorio de Inmunovirología

  • Magister en Ciencias Biológicas. Opción Bioquímica. PEDECIBA-Facultad de Ciencias-Universidad de la República, 1992.

  • Doctor en Ciencias. Opción Inmunología Fundamental, Universidad Diderot París 7 – Instituto Pasteur de París, 1997.

  • Inmunología Molecular

  • Virología molecular

  • Interacciónes moleculares

  • Inmunotecnología

  • Biofísica de proteínas

  • Conformational plasticity of the native retroviral capsid revealed by X ray crystallography. Obal G, Trajtenberg F, Carrión F, Tomé L, Larrieux N, Zhang X, Pritsch O, Buschiazzo A. Science 349(6243):95-98, 2015

  • Search for an aetiological virus candidate in chronic lymphocytic leukaemia by extensive transcriptome analysis. Rego N, Bianchi S, Moreno P, Persson H, Kvist A, Pena A, Oppezzo P, Naya H, Rovira C, Dighiero G, Pritsch O. British Journal of Haematology 157(6):709-17, 2012.

  • Immunoglobulin heavy chain V-D-J gene rearrangement and mutational status in Uruguayan patients with chronic lymphocytic leukemia. Bianchi S, Moreno P, Landoni AI, Naya H, Oppezzo P, Dighiero G, Gabús R, Pritsch O. Leukemia & Lymphoma 51 (11): 2070-2078, 2010.

  • Phylogenetic analysis of bovine leukemia viruses isolated in South America reveals diversification in seven distinct genotypes. Moratorio G, Obal G, Dubra A, Correa A, Bianchi S, Buschiazzo A, Cristina J, Pritsch O. Archives of Virology 155(4):481-9. 2010.

  • Post-transcriptional regulation of Inducible Nitric Oxide Synthase in Chronic Lymphocytic Leukemia B cells in pro-apoptotic and anti-apoptotic culture conditions. Tiscornia, A.; Cayota, A.; Landoni A.I.; Brito, C.;Oppezzo, P.; Vuillier, F.; Robello, C.; Dighiero, G.; Gabús, R.; Pritsch, O. Leukemia 18: 48-56, 2004

  • Production and functional characterization of two mouse/human chimeric antibodies with specificity for the tumor-associated Tn antigen. Oppezzo, P.; Osinaga, E.; Tello, D.; Bay, S.; Cantacuzene, D.; Irigoín, F.; Ferreira, A.; Cayota, A.; Alzari, P. and Pritsch, O. Hybridoma, 19: 229-240, 2000.

  • Expression of Unmutated VH Genes is a Detrimental Prognostic Factor in Chronic Lymphocytic Leukemia. Maloum, K.; Pritsch, O.; Magnac, C.; Vuillier, F.; Davi, F.; Troussard, X.; Mauro, F.R.; Bénichou, J.; Merle-Béral, H. and Dighiero, G. Blood, 96: 377-379, 2000.

  • Can Immunoglobulin CH1 constant region domain modulate antigen binding affinity of antibodies? Pritsch, O.; Hudry-Clergeon, G.; Buckle, M.; Pétillot, Y.; Bouvet, J.P.; Gagnon, J.; Dighiero, G. Journal of Clinical Investigation 98, 2235-2243, 1996.