{"id":5164,"date":"2022-04-01T20:23:20","date_gmt":"2022-04-01T20:23:20","guid":{"rendered":"https:\/\/pasteur.uy\/heads-of-labs-and-units\/nicolas-sarute\/"},"modified":"2022-12-13T14:10:32","modified_gmt":"2022-12-13T14:10:32","slug":"nicolas-sarute","status":"publish","type":"page","link":"https:\/\/pasteur.uy\/en\/heads-of-labs-and-units\/nicolas-sarute\/","title":{"rendered":"Nicol\u00e1s Sarute"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_last_edited=&#8221;off|desktop&#8221; custom_padding=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,2_3&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;2&#8243; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;75%&#8221; custom_margin=&#8221;||||false|false&#8221; custom_margin_tablet=&#8221;||||false|false&#8221; custom_margin_phone=&#8221;||||false|false&#8221; custom_margin_last_edited=&#8221;on|desktop&#8221; custom_padding=&#8221;||10px||false|false&#8221; animation_style=&#8221;fade&#8221; animation_duration=&#8221;300ms&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_3&#8243; _builder_version=&#8221;4.14.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/09\/Sarute-Nicolas.jpg&#8221; title_text=&#8221;Sarute, Nicol\u00e1s&#8221; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;75%&#8221; hover_enabled=&#8221;0&#8243; global_colors_info=&#8221;{}&#8221; sticky_enabled=&#8221;0&#8243;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;2_3&#8243; _builder_version=&#8221;4.14.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; text_font=&#8221;|700|||||||&#8221; text_font_size=&#8221;21px&#8221; header_font=&#8221;|700|||||||&#8221; header_text_color=&#8221;#005293&#8243; header_font_size=&#8221;39px&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_padding=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1>Nicol\u00e1s Sarute<\/h1>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_padding=&#8221;||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p class=\"et_pb_member_position et-fb-editable-element et-fb-editable-element__editing\" data-shortcode-id=\"0.0.0.0-1643373697362\" data-quickaccess-id=\"position\" contenteditable=\"true\">\n            <span>Nicol\u00e1s Sarute, PhD<\/span>\n          <\/p>\n<div data-shortcode-id=\"0.0.0.0-1643374141066\" data-quickaccess-id=\"body\" data-quickaccess-editable=\"yes\" class=\"et-fb-popover-tinymce\">\n<div class=\"mce-content-body\" contenteditable=\"true\" style=\"position: relative;\">\n<p>\n                <a href=\"mailto:nsarute@pasteur.edu.uy\">nsarute@pasteur.edu.uy<\/a>\n              <\/p>\n<\/p><\/div>\n<\/p><\/div>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;#ce8e00&#8243; 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custom_padding=&#8221;||||false|false&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>Laboratory of<br \/>Virus-Cell Interactions<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; animation_style=&#8221;fade&#8221; animation_duration=&#8221;500ms&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row column_structure=&#8221;1_3,1_3,1_3&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;1&#8243; custom_padding_last_edited=&#8221;on|phone&#8221; module_class=&#8221;df-buttons &#8221; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;75%&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_margin_tablet=&#8221;||0px||false|false&#8221; custom_margin_phone=&#8221;||0px||false|false&#8221; custom_margin_last_edited=&#8221;on|phone&#8221; custom_padding=&#8221;18px||0px||false|false&#8221; 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_builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; custom_button=&#8221;on&#8221; button_text_size=&#8221;16px&#8221; button_text_color=&#8221;#005293&#8243; button_bg_color=&#8221;rgba(0,82,147,0.16)&#8221; button_border_width=&#8221;0px&#8221; button_border_color=&#8221;#005293&#8243; button_border_radius=&#8221;0px&#8221; button_font=&#8221;|700|||||||&#8221; button_use_icon=&#8221;off&#8221; transform_scale=&#8221;97%|97%&#8221; custom_padding=&#8221;10px||10px||false|false&#8221; custom_css_main_element=&#8221;width: 100% !important;&#8221; global_colors_info=&#8221;{}&#8221; button_text_color__hover_enabled=&#8221;on|desktop&#8221; button_text_color__hover=&#8221;#FFFFFF&#8221; button_bg_color__hover_enabled=&#8221;on|hover&#8221; button_bg_color__hover=&#8221;#005293&#8243; button_bg_enable_color__hover=&#8221;on&#8221;][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; module_class=&#8221;df-rows df-area dfc-educacion&#8221; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;0px||||false|false&#8221; custom_padding=&#8221;15px||||false|false&#8221; animation_style=&#8221;fade&#8221; animation_duration=&#8221;600ms&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row module_class=&#8221;dfc-educacion&#8221; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;75%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;|21px||21px|false|true&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Postdoctoral Researcher in Virus-Host Interactions. Department of Microbiology, School of Medicine, University of Pennsylvania (2015-2016); Department of Microbiology and Immunology, School of Medicine, University of Illinois at Chicago (2016-2020).<\/li>\n<li>Doctor in Biological Sciences Genetic Option, PEDECIBA. Evolutionary Genetics Section, Faculty of Sciences, UdelaR in collaboration with the Viral Populations and Pathogenesis laboratory, Institut Pasteur Paris (2012-2014)<\/li>\n<li>MSc. in Biological Sciences Genetic Option, PEDECIBA. Evolutionary Genetics Section, Faculty of Sciences, UdelaR (2008-2011).<\/li>\n<li>Degree in Biological Sciences Deepening in Genetics, Faculty of Science, UdelaR (2003-2008).<\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_class=&#8221;dfc-areas&#8221; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;75%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;|21px||21px|false|true&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Cell virology<\/li>\n<li>Signal transduction<\/li>\n<li>Antiviral immune response<\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_class=&#8221;dfc-publicaciones&#8221; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; max_width=&#8221;75%&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.14.6&#8243; _module_preset=&#8221;default&#8221; ul_line_height=&#8221;1.7em&#8221; width=&#8221;100%&#8221; custom_padding=&#8221;|21px||21px|false|true&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Sarute N, Cheng H, Yan Z, Salas-Briceno K, Richner J, Rong L, Ross SR (2021). Signal-regulatory protein alpha is an anti-viral entry factor targeting viruses using endocytic pathways. PLoS Pathog. 17(6):e1009662. https:\/\/doi.org\/10.1371\/journal.ppat.1009662<\/li>\n<li>Sarute N, Ross SR (2021). The board is set, the pieces are moving: Modulation of New World arenavirus entry by host proteins. PLoS Pathog. 17(6):e1009605. https:\/\/doi.org\/10.1371\/journal.ppat.1009605<\/li>\n<li>Sarute N, Ross SR (2020). CACNA1S haploinsufficiency confers resistance to New World arenavirus infection. Proc Natl Acad Sci USA. 117(32): 19497-19506. https:\/\/doi.org\/10.1073\/pnas.1920551117.<\/li>\n<li>Li* JJ, Sarute* N, Lancaster E, Otkiran-Clare G, et al (2020). A recessive Trim2 mutation causes an axonal neuropathy in mice. Neurobiol Dis, 140:104845. https:\/\/doi.org\/10.1016\/j.nbd.2020.104845. *Co-first<\/li>\n<li>Sarute N, Ibrahim N, Medegan Fagla B, et al (2019). TRIM2, a novel member of the antiviral family, limits new world arenavirus entry. PLoS Biol 17 (2): e3000137. https:\/\/doi.org\/10.1371\/journal.pbio.3000137.<\/li>\n<li>Sarute N, Ross SR (2017). New World Arenavirus Biology. Annual Reviews of Virology, 4(1):141-158. doi: 10.1146\/annurev-virology-101416-042001.<\/li>\n<\/ul>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Nicol\u00e1s Sarute Nicol\u00e1s Sarute, PhD nsarute@pasteur.edu.uy Laboratory ofVirus-Cell Interactions Postdoctoral Researcher in Virus-Host Interactions. Department of Microbiology, School of Medicine, University of Pennsylvania (2015-2016); Department of Microbiology and Immunology, School of Medicine, University of Illinois at Chicago (2016-2020). Doctor in Biological Sciences Genetic Option, PEDECIBA. Evolutionary Genetics Section, Faculty of Sciences, UdelaR in collaboration with [&hellip;]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":3590,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"dipi_cpt_category":[],"class_list":["post-5164","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/pages\/5164","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/comments?post=5164"}],"version-history":[{"count":5,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/pages\/5164\/revisions"}],"predecessor-version":[{"id":8414,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/pages\/5164\/revisions\/8414"}],"up":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/pages\/3590"}],"wp:attachment":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/media?parent=5164"}],"wp:term":[{"taxonomy":"dipi_cpt_category","embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/dipi_cpt_category?post=5164"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}