{"id":5269,"date":"2022-04-04T17:52:27","date_gmt":"2022-04-04T17:52:27","guid":{"rendered":"https:\/\/pasteur.uy\/heads-of-labs-and-units\/carlos-batthyany\/"},"modified":"2022-04-04T18:32:49","modified_gmt":"2022-04-04T18:32:49","slug":"carlos-batthyany","status":"publish","type":"page","link":"https:\/\/pasteur.uy\/en\/heads-of-labs-and-units\/carlos-batthyany\/","title":{"rendered":"Carlos Batthy\u00e1ny"},"content":{"rendered":"

[et_pb_section fb_built=”1″ _builder_version=”4.14.6″ _module_preset=”default” custom_margin=”||||false|false” custom_margin_last_edited=”off|desktop” custom_padding=”||0px||false|false” global_colors_info=”{}”][et_pb_row column_structure=”1_3,2_3″ use_custom_gutter=”on” gutter_width=”2″ _builder_version=”4.14.6″ _module_preset=”default” max_width=”75%” custom_margin=”||||false|false” custom_margin_tablet=”||||false|false” custom_margin_phone=”||||false|false” custom_margin_last_edited=”on|desktop” custom_padding=”||10px||false|false” animation_style=”fade” animation_duration=”300ms” global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.14.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_image src=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/01\/Batthyany-Carlos-1.jpeg” title_text=”Batthyany, Carlos” _builder_version=”4.14.6″ _module_preset=”default” max_width=”75%” global_colors_info=”{}”][\/et_pb_image][\/et_pb_column][et_pb_column type=”2_3″ _builder_version=”4.14.4″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.14.6″ _module_preset=”default” text_font=”|700|||||||” text_font_size=”21px” header_font=”|700|||||||” header_text_color=”#005293″ header_font_size=”39px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” global_colors_info=”{}”]<\/p>\n

Carlos Batthy\u00e1ny<\/h1>\n

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PhD, MD Carlos Batty\u00e1ny<\/p>\n

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\n battyany@pasteur.edu.uy<\/a>\n <\/p>\n<\/p><\/div>\n<\/p><\/div>\n

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Vascular Biology and
Drug Development Laboratory<\/p>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ _builder_version=”4.14.6″ _module_preset=”default” custom_padding=”0px||0px||false|false” animation_style=”fade” animation_duration=”500ms” global_colors_info=”{}”][et_pb_row column_structure=”1_3,1_3,1_3″ use_custom_gutter=”on” gutter_width=”1″ custom_padding_last_edited=”on|phone” module_class=”df-buttons ” _builder_version=”4.14.6″ _module_preset=”default” max_width=”75%” custom_margin=”||0px||false|false” custom_margin_tablet=”||0px||false|false” custom_margin_phone=”||0px||false|false” custom_margin_last_edited=”on|phone” custom_padding=”18px||0px||false|false” custom_padding_tablet=”18px||0px||false|false” custom_padding_phone=”2px||||false|false” border_width_bottom=”1px” border_color_bottom=”#005293″ global_colors_info=”{}”][et_pb_column type=”1_3″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_button button_text=”Education” button_alignment=”center” button_text_tablet=”Education” button_text_phone=”Education” button_text_last_edited=”on|desktop” module_class=”df-button dfc-educacion” _builder_version=”4.14.6″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#005293″ button_bg_color=”rgba(0,82,147,0.16)” button_border_width=”0px” button_border_color=”#005293″ button_border_radius=”0px” button_font=”|700|||||||” button_use_icon=”off” transform_scale=”97%|97%” custom_padding=”10px||10px||false|false” custom_css_main_element=”width: 100% !important;” global_colors_info=”{}” button_text_color__hover_enabled=”on|desktop” button_text_color__hover=”#FFFFFF” button_bg_color__hover_enabled=”on|hover” button_bg_color__hover=”#005293″ button_bg_enable_color__hover=”on”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_button button_text=”Research areas” button_alignment=”center” module_class=”dfc-areas df-button” _builder_version=”4.14.6″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#005293″ button_bg_color=”rgba(0,82,147,0.16)” button_border_width=”0px” button_border_color=”#005293″ button_border_radius=”0px” button_font=”|700|||||||” button_use_icon=”off” transform_scale=”97%|97%” custom_padding=”10px||10px||false|false” custom_css_main_element=”width: 100% !important;” global_colors_info=”{}” button_text_color__hover_enabled=”on|desktop” button_text_color__hover=”#FFFFFF” button_bg_color__hover_enabled=”on|hover” button_bg_color__hover=”#005293″ button_bg_enable_color__hover=”on”][\/et_pb_button][\/et_pb_column][et_pb_column type=”1_3″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_button button_text=”Relevant publications” button_alignment=”center” module_class=”dfc-publicaciones df-button” _builder_version=”4.14.6″ _module_preset=”default” custom_button=”on” button_text_size=”16px” button_text_color=”#005293″ button_bg_color=”rgba(0,82,147,0.16)” button_border_width=”0px” button_border_color=”#005293″ button_border_radius=”0px” button_font=”|700|||||||” button_use_icon=”off” transform_scale=”97%|97%” custom_padding=”10px||10px||false|false” custom_css_main_element=”width: 100% !important;” global_colors_info=”{}” button_text_color__hover_enabled=”on|desktop” button_text_color__hover=”#FFFFFF” button_bg_color__hover_enabled=”on|hover” button_bg_color__hover=”#005293″ button_bg_enable_color__hover=”on”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ module_class=”df-rows df-area dfc-educacion” _builder_version=”4.14.6″ _module_preset=”default” custom_margin=”0px||||false|false” custom_padding=”15px||||false|false” animation_style=”fade” animation_duration=”600ms” global_colors_info=”{}”][et_pb_row module_class=”dfc-educacion” _builder_version=”4.14.6″ _module_preset=”default” max_width=”75%” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.14.6″ _module_preset=”default” width=”100%” custom_padding=”|21px||21px|false|true” global_colors_info=”{}”]<\/p>\n

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  • Postdoctoral Research Fellow and Research Fellow, Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA. Research area: drug development for conditions related to inflammation. (2006-2007).<\/li>\n
  • Postdoctoral Fellow, Center for Free Radical Biology, University of Alabama at Birmingham, AL, USA. Research area: Free Radical Biology and Inflammatory Mediators. (2004-2006).<\/li>\n
  • Ph.D in Biochemistry, Faculty of Science (Udelar) and Pedeciba, Uruguay. Dissertation: \u201cInflammatory oxidants and atherosclerosis: role of nitric oxide-derived species\u201d (2005).<\/li>\n
  • MSc. in Biochemistry, Faculty of Science (Udelar), Pedeciba, Uruguay. Dissertation: \u201cAmino acid sequence and three-dimensional structure of Tn-specific isolectin B4 from Vicia villosa\u201d (1997).<\/li>\n
  • Doctor of Medicine (MD), Faculty of Medicine, University of the Republic, Uruguay (1996).<\/li>\n<\/ul><\/div>\n

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    \n
      \n
    • Vascular biology<\/li>\n
    • Drug development<\/li>\n
    • Inflammation related diseases<\/li>\n
    • Pharmacology<\/li>\n
    • Transgenesis<\/li>\n
    • Atherosclerosis<\/li>\n<\/ul><\/div>\n

      [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”dfc-publicaciones” _builder_version=”4.14.6″ _module_preset=”default” max_width=”75%” global_colors_info=”{}”][et_pb_column type=”4_4″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}”][et_pb_text _builder_version=”4.14.6″ _module_preset=”default” ul_line_height=”1.7em” width=”100%” custom_padding=”|21px||21px|false|true” global_colors_info=”{}”]<\/p>\n

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      • Batthyany, C., Souza JM, Dur\u00e1n R, Cassina A, Cerve\u00f1ansky C and Radi R. Time course and site(s) of cytochrome c tyrosine nitration by peroxynitrite. Biochemistry 44, 8038-8046, 2005.<\/li>\n
      • Batthyany, C., Schopfer, F. J., Baker, P. R., Duran, R., Baker, L. M., Huang, Y., Cervenansky, C., Branchaud, B. P., and Freeman, B. A. Reversible post-translational modification of proteins by nitrated fatty acids in vivo. J Biol Chem 281, 20450-63, 2006.<\/li>\n
      • Batthyany, C., Kelley, E. E., Hundley, N. J., Woodcock, S. R., Bonacci, G., Del Rio, J. M., Schopfer, F. J., Lancaster, J. R., Jr., Freeman, B. A., and Tarpey, M. M. Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase. J Biol Chem 283, 36176-84, 2008 (co-first author).<\/li>\n
      • Schopfer, F. J., Batthyany, C., Baker, P. R., Bonacci, G., Cole, M. P., Rudolph, V., Groeger, A. L., Rudolph, T. K., Nadtochiy, S., Brookes, P. S., and Freeman, B. A. Detection and quantification of protein adduction by electrophilic fatty acids: mitochondrial generation of fatty acid nitroalkene derivatives. Free Radic Biol Med 46, 1250-9, 2009.<\/li>\n
      • Khoo, N. K., Rudolph, V., Cole, M. P., Golin-Bisello, F., Schopfer, F. J., Woodcock, S. R., Batthy\u00e1ny, C. & Freeman, B. A. Activation of vascular endothelial nitric oxide synthase and heme oxygenase-1 expression by electrophilic nitro-fatty acids. Free radical biology & medicine 48, 230-239, doi:10.1016\/j.freeradbiomed.2009.10.046 (2010).<\/li>\n
      • Bonacci, G., Schopfer, F. J., Batthy\u00e1ny, C., Rudolph, T. K., Rudolph, V., Khoo, N. K., Kelley, E. E. & Freeman, B. A. Electrophilic fatty acids regulate matrix metalloproteinase activity and expression. The Journal of biological chemistry 286, 16074-16081, doi:10.1074\/jbc.M111.225029 (2011).<\/li>\n
      • Gil, M., Grana, M., Schopfer, F. J., Wagner, T., Denicola, A., Freeman, B. A., Alzari, P. M., Batthy\u00e1ny, C. & Duran, R. Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe-S center. Free radical biology & medicine 65, 150-161, doi:10.1016\/j.freeradbiomed.2013.06.021 (2013).<\/li>\n
      • Batthy\u00e1ny, C., Bartesaghi, S., Mastrogiovanni, M., Lima, A., Demicheli, V. & Radi, R. Tyrosine-Nitrated Proteins: Proteomic and Bioanalytical Aspects. Antioxidants & redox signaling, doi:10.1089\/ars.2016.6787 (2016).<\/li>\n<\/ul>\n

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        Carlos Batthy\u00e1nyPhD, MD Carlos Batty\u00e1ny battyany@pasteur.edu.uy Vascular Biology and Drug Development Laboratory Postdoctoral Research Fellow and Research Fellow, Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA. Research area: drug development for conditions related to inflammation. (2006-2007). Postdoctoral Fellow, Center for Free Radical Biology, University of Alabama at Birmingham, […]<\/p>\n","protected":false},"author":8,"featured_media":0,"parent":3590,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"dipi_cpt_category":[],"class_list":["post-5269","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/pages\/5269","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/comments?post=5269"}],"version-history":[{"count":5,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/pages\/5269\/revisions"}],"predecessor-version":[{"id":5319,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/pages\/5269\/revisions\/5319"}],"up":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/pages\/3590"}],"wp:attachment":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/media?parent=5269"}],"wp:term":[{"taxonomy":"dipi_cpt_category","embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/dipi_cpt_category?post=5269"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}