[et_pb_section fb_built=”1″ _builder_version=”4.16″ _module_preset=”default” custom_padding=”9px||0px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row _builder_version=”4.16″ _module_preset=”default” max_width=”80%” custom_margin=”|auto|0px|auto|false|false” custom_padding=”||0px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” text_font=”Titillium Web|700|||||||” header_font=”Titillium Web|700|||||||” header_text_color=”#005293″ header_font_size=”44px” custom_margin=”||22px|||” header_font_size_tablet=”38px” header_font_size_phone=”29px” header_font_size_last_edited=”on|phone” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.16″ _module_preset=”default” max_width=”80%” custom_padding=”||49px|||” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n
The unit provides high-level support in the field of animal genome modification (mice, rats and ruminants). We offer several techniques, such as pronuclear microinjection, homologous recombination in embryonic stem cells, lentiviral injection, transposons and the revolutionary CRISPR \/ Cas9 system. We also provide cryopreservation, in vitro fertilization and embryo rederivation in mice. Besides, the unit supplies mice and rats with high genetic and health status for researchers within the institute and the region.<\/p>\n
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Since 2007 we have worked with national and international biotechnology companies offering in vivo biological assays in mice and rats, under GLP standards.<\/p>\n
[\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n
We receive undergraduate and graduate students who do thesis using different technologies to obtain animal models. We also organize courses for technicians and scientists, and offer internships for technicians or veterinarians who administer their own services.<\/p>\n
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Our staff is member of organizations, such as the International Society for Transgenic Technologies (ISTT), the Institutional Articulation Committee (CAI), the National Commission of Animal Experimentation (CNEA), the Uruguayan Association of Animal Science and Technology Laboratories (AUCyTAL), and the Federation of South American Associations for Laboratory Animal Science (FESSACAL).<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” _builder_version=”4.16″ _module_preset=”default” custom_padding=”0px||0px|0px|false|false” border_color_bottom=”#005293″ global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row column_structure=”1_6,1_6,1_6,1_6,1_6,1_6″ use_custom_gutter=”on” gutter_width=”1″ _builder_version=”4.16″ _module_preset=”default” width=”100%” max_width=”80%” custom_padding=”0px||0px||false|false” border_width_bottom=”1px” border_color_bottom=”#005293″ global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”1_6″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_button button_text=”Members” button_alignment=”center” module_class=”df-button dfc-integrantes” _builder_version=”4.16″ _module_preset=”default” custom_button=”on” button_text_size=”14px” button_text_color=”#005293″ 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custom_css_main_element=”width: 100% !important;” global_colors_info=”{}” button_text_color__hover_enabled=”on|desktop” button_text_color__hover=”#FFFFFF” button_bg_color__hover_enabled=”on|hover” button_bg_color__hover=”#005293″ button_bg_enable_color__hover=”on” theme_builder_area=”post_content”][\/et_pb_button][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=”1″ disabled_on=”off|off|off” module_class=”df-area df-rows dfc-integrantes” _builder_version=”4.16″ _module_preset=”default” custom_padding=”16px|||||” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_row module_class=”dfc-integrantes” _builder_version=”4.16″ _module_preset=”default” width_tablet=”” width_phone=”auto” width_last_edited=”on|phone” max_width=”80%” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ module_class=”dfc-humano” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” header_2_font=”|700|||||||” header_2_text_color=”#005293″ header_2_font_size=”35px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” header_2_font_size_tablet=”35px” header_2_font_size_phone=”29px” header_2_font_size_last_edited=”on|phone” saved_tabs=”all” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n
[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ use_custom_gutter=”on” gutter_width=”2″ module_class=”dfc-integrantes” _builder_version=”4.16″ _module_preset=”default” width_tablet=”” width_phone=”auto” width_last_edited=”on|phone” max_width=”80%” custom_padding=”||6px|||” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”1_4″ module_class=”dfc-humano” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Martina Crispo, DVM, PhD” position=”Head ” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2025\/02\/Mart.jpg” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” link_option_url=”https:\/\/pasteur.uy\/en\/heads-of-labs-and-units\/martina-crispo\/” link_option_url_new_window=”on” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n
crispo@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Geraldine Schlapp, MSc” position=”Senior Associate Technician” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/02\/Schlapp-Geraldine.jpg” _builder_version=”4.16″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n PhD student [\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ module_class=”dfc-humano” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Jorge P\u00f3rfido, PhD” position=”Senior Associate Technician” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2025\/12\/Jorge-porfido.png” _builder_version=”4.27.5″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n jlporfido@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Ana Paula Ar\u00e9valo, MSc” position=”Deputy technitian” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/02\/Arevalo-Ana-Paula.jpg” _builder_version=”4.16″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n PhD student [\/et_pb_team_member][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ use_custom_gutter=”on” gutter_width=”2″ module_class=”dfc-integrantes” _builder_version=”4.16″ _module_preset=”default” width_tablet=”” width_phone=”auto” width_last_edited=”on|phone” max_width=”80%” custom_padding=”||6px|||” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”1_4″ module_class=”dfc-humano” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Gabriel Fern\u00e1ndez, BSc” position=”Deputy technician” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/02\/Fernandez-Gabriel.jpg” _builder_version=”4.16″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” link_option_url_new_window=”on” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n gabifergra@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Ismael Gonz\u00e1lez” position=”Ayudante t\u00e9cnico” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2025\/03\/Ismael-Gonzalez-1.jpg” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n igonzalez@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ module_class=”dfc-humano” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Mar\u00eda Noel Meikle, MSc” position=”Deputy technitian” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/02\/Meikele-Maria-Noel.jpg” _builder_version=”4.27.5″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” hover_enabled=”0″ global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content” sticky_enabled=”0″]<\/p>\n PhD student [\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Marcela Souza, DVM” position=”Master's degree student” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/02\/icono-persona.jpg” _builder_version=”4.16″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n msouza@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_team_member][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ use_custom_gutter=”on” gutter_width=”2″ module_class=”dfc-integrantes” _builder_version=”4.16″ _module_preset=”default” width_tablet=”” width_phone=”auto” width_last_edited=”on|phone” max_width=”80%” custom_padding=”||6px|||” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”1_4″ module_class=”dfc-humano” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Sergio Ancheta” position=”Technical assistant” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/02\/Ancheta-Sergio.jpg” _builder_version=”4.16″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” link_option_url_new_window=”on” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n sergioancheta@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_team_member][et_pb_team_member name=”Judith Raymond” position=”Technical assistant” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2025\/05\/Judith-Raymond.jpg” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” link_option_url_new_window=”on” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n jraymond@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Jes\u00fas Parada” position=”Technical assistant” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2024\/02\/Parada-Jesus-1.jpg” _builder_version=”4.16″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n jparada@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ module_class=”dfc-humano” _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Andrea Massa” position=”Technical assistant” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/02\/Massa-Andrea.jpg” _builder_version=”4.16″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n amassa@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_team_member name=”Meribeth Santana” position=”Technical assistant” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/02\/icono-persona.jpg” _builder_version=”4.27.4″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”post_content”]<\/p>\n msantana@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_team_member][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”dfc-investigacion” _builder_version=”4.16″ _module_preset=”default” max_width=”80%” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” header_2_font=”|700|||||||” header_2_text_color=”#005293″ header_2_font_size=”35px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” header_2_font_size_tablet=”35px” header_2_font_size_phone=”29px” header_2_font_size_last_edited=”on|phone” saved_tabs=”all” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ _module_preset=”default” custom_padding=”27px|||||” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n Gene editing in<\/strong> rodents <\/strong>.<\/p>\n <\/p>\n Gene editing in<\/strong> ruminants<\/strong>.<\/p>\n <\/p>\n Cryopreservation <\/strong> of embryos and mammals sperm.<\/p>\n <\/p>\n In vitro fertilization<\/strong> of rodents and ruminants.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”dfc-equipos” _builder_version=”4.16″ _module_preset=”default” max_width=”80%” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” header_2_font=”|700|||||||” header_2_text_color=”#005293″ header_2_font_size=”35px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” header_2_font_size_tablet=”35px” header_2_font_size_phone=”29px” header_2_font_size_last_edited=”on|phone” saved_tabs=”all” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ _module_preset=”default” custom_padding=”27px|||||” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n <\/p>\n <\/p>\n <\/p>\n <\/p>\n <\/p>\n <\/p>\n <\/p>\n <\/p>\n For further information, please contact ubal@pasteur.edu.uy<\/a><\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”dfc-servicios” _builder_version=”4.16″ _module_preset=”default” max_width=”80%” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” header_2_font=”|700|||||||” header_2_text_color=”#005293″ header_2_font_size=”35px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” header_2_font_size_tablet=”35px” header_2_font_size_phone=”29px” header_2_font_size_last_edited=”on|phone” saved_tabs=”all” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n [\/et_pb_text][et_pb_text _builder_version=”4.16″ _module_preset=”default” custom_padding=”27px|||||” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”dfc-proyectos” _builder_version=”4.16″ _module_preset=”default” max_width=”80%” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” header_2_font=”|700|||||||” header_2_text_color=”#005293″ header_2_font_size=”35px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” header_2_font_size_tablet=”35px” header_2_font_size_phone=”29px” header_2_font_size_last_edited=”on|phone” saved_tabs=”all” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ module_class=”dfc-proyectos” _builder_version=”4.16″ _module_preset=”default” max_width=”80%” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” custom_margin=”||0px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n 2022- … <\/strong>\u2013 Evaluation of the combination of racotumomab with immunological checkpoint inhibitors in syngeneic murine models of NeuGc expression <\/p>\n 2021- … <\/strong>\u2013 Preclinical development of a nanotechnology-based aerosol with tocilizumab to fight COVID-19<\/p>\n <\/p>\n 2020- … <\/strong>\u2013 Mini-intestines: a powerful in vitro tool for replacement of experimental animals <\/p>\n 2015\u20102018<\/strong> \u2013 New strategies for the cryopreservation of oocytes and ovine embryos produced in vitro.<\/p>\n <\/p>\n 2015\u20102018<\/strong> \u2013 Development of inoculants for the mobilization of phosphorus as an input in agricultural production. Participation: researcher.<\/p>\n <\/p>\n 2015\u20102018<\/strong> \u2013 Development and validation of processes for the study and valuation of nutraceuticals: creation of the first Uruguayan company. Participation: researcher.<\/p>\n <\/p>\n 2016-2019<\/strong> \u2013 Design and production of new variants of the follicle stimulating hormone (FSH) for its use in species of productive interest. Participation: researcher.<\/p>\n <\/p>\n 2012-2016<\/strong> \u2013 Study of the mechanisms responsible for the potential probiotic effects of the CNCM I-3690 Lactobacillus rhamnosus strain.<\/p>\n <\/p>\n 2014-2016<\/strong> \u2013 Evaluation by molecular imaging of the anti-Tn diabody in the murine model of lung cancer. Master\u2019s Thesis.<\/p>\n [\/et_pb_text][\/et_pb_column][et_pb_column type=”1_2″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” custom_margin=”3px|||||” custom_padding=”0px||||false|false” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n 2014-2016<\/strong> \u2013 Influence of progesterone on follicular development on oocyte maturation and fertility in sheep. Master\u2019s Thesis.<\/p>\n <\/p>\n 2014-2016<\/strong> \u2013 Effect of lipid content on the maturation and vitrification of oocytes ovine: Mechanism of action and its application to the production of in vitro embryos.<\/p>\n <\/p>\n 2012-2014<\/strong> \u2013 Cryopreservation of ovine embryos produced in vitro in different stages by means of two vitrification methods. Master\u2019s Thesis.<\/p>\n <\/p>\n 2013-2014<\/strong> \u2013 Characterization of an inducible murine model for the study of insulin signaling pathways. Initiation scholarship in the investigation.<\/p>\n <\/p>\n 2013-2014<\/strong> \u2013 Derivation and characterization of a line of murine embryonic stem cells (ESC) Oct4-GFP in the absence of serum and murine embryonic fibroblasts (MEF). Initiation scholarship in the investigation.<\/p>\n <\/p>\n 2011-2014<\/strong> \u2013 A technological innovation for sheep reproduction in Uruguay: in vitro production of embryos and their large-scale application.<\/p>\n <\/p>\n 2012-2014<\/strong> \u2013 Applied environmental toxicology: risk evaluation to environmental anthropogenic estrogen exposure in a transgenic murine model Oct4-GFP. Collaboration.<\/p>\n [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”dfc-publicaciones” _builder_version=”4.16″ _module_preset=”default” max_width=”80%” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_column type=”4_4″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_text _builder_version=”4.16″ _module_preset=”default” header_2_font=”|700|||||||” header_2_text_color=”#005293″ header_2_font_size=”35px” custom_margin=”||0px||false|false” custom_padding=”||26px||false|false” header_2_font_size_tablet=”35px” header_2_font_size_phone=”29px” header_2_font_size_last_edited=”on|phone” saved_tabs=”all” global_colors_info=”{}” theme_builder_area=”post_content”]<\/p>\n [\/et_pb_text][et_pb_accordion icon_color=”#005293″ _builder_version=”4.16″ _module_preset=”default” toggle_text_color=”#005293″ toggle_font=”Titillium Web|600|||||||” toggle_font_size=”17px” custom_margin=”||||false|false” global_colors_info=”{}” theme_builder_area=”post_content”][et_pb_accordion_item title=”vacio” open=”on” _builder_version=”4.16″ _module_preset=”default” custom_css_main_element=”display:none” global_colors_info=”{}” theme_builder_area=”post_content”][\/et_pb_accordion_item][et_pb_accordion_item title=”2024″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2023″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2022″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2021″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2020″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2019″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2018″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2017″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2016″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2015″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2014″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2013″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2010″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][et_pb_accordion_item title=”2007″ _builder_version=”4.16″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”post_content” open=”off”]<\/p>\n [\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":" Laboratory Animals BiotechnologyThe unit provides high-level support in the field of animal genome modification (mice, rats and ruminants). We offer several techniques, such as pronuclear microinjection, homologous recombination in embryonic stem cells, lentiviral injection, transposons and the revolutionary CRISPR \/ Cas9 system. We also provide cryopreservation, in vitro fertilization and embryo rederivation in mice. Besides, […]<\/p>\n","protected":false},"author":8,"featured_media":3376,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[59],"tags":[],"dipi_cpt_category":[],"class_list":["post-4464","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-units"],"acf":[],"_links":{"self":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/posts\/4464","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/comments?post=4464"}],"version-history":[{"count":5,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/posts\/4464\/revisions"}],"predecessor-version":[{"id":24854700,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/posts\/4464\/revisions\/24854700"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/media\/3376"}],"wp:attachment":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/media?parent=4464"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/categories?post=4464"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/tags?post=4464"},{"taxonomy":"dipi_cpt_category","embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/dipi_cpt_category?post=4464"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
gschlapp@pasteur.edu.uy<\/a><\/p>\n
aparevalo@pasteur.edu.uy<\/a><\/p>\n
manomeikle@pasteur.edu.uy<\/a><\/p>\nResearch lines<\/h2>\n
Main equipment<\/h2>\n
FACILITIES<\/h3>\n
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ACTIVITIES<\/h3>\n
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Courses<\/h2>\n
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Projects<\/h2>\n
syngeneic murine models of NeuGc expression<\/p>\n
<\/strong><\/p>\nMain publications<\/h2>\n
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Calzada. In Vivo Evaluation of Sgc8-c Aptamer as a Molecular Imaging Probe for Colon Cancer in a Mouse Xenograft Model. International Journal of Molecular Sciences, v.: 23 p.:2466 2022. DOI: 10.3390\/ijms23052466 http:\/\/dx.doi.org\/10.3390\/ijms23052466<\/a><\/li>\n
Santos Neto , Marcela Souza Neves , Federico Cuadro , Richard Nu\u00f1ez Olivera, Martina Crispo , F\u00e1bio R. Vasconcelos , Maria Julia B. Bezerra , Renato F. Silva , Laritza F. Lima , Jos\u00e9 Ricardo Figueiredo , Ivan C. Bustamante Filho, Alejo Menchaca, Arlindo A. Moura. How in vitro maturation changes the proteome of ovine cumulusoocyte complexes. Molecular Reproduction and Development, 2022. DOI: 10.1002\/mrd.23638 http:\/\/dx.doi.org\/10.1002\/mrd.23638<\/li>\n<\/ul>\n\n
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