{"id":5428,"date":"2022-04-04T20:35:58","date_gmt":"2022-04-04T20:35:58","guid":{"rendered":"https:\/\/pasteur.uy\/uncategorized\/signal-processing\/"},"modified":"2022-04-04T20:36:03","modified_gmt":"2022-04-04T20:36:03","slug":"signal-processing","status":"publish","type":"post","link":"https:\/\/pasteur.uy\/en\/previous-laboratories\/signal-processing\/","title":{"rendered":"Signal Processing"},"content":{"rendered":"

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Signal Processing<\/h1>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_2,1_2″ _builder_version=”4.14.6″ _module_preset=”default” max_width=”80%” custom_padding=”||49px|||” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_column type=”1_2″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_text _builder_version=”4.14.6″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”et_body_layout” sticky_enabled=”0″]<\/p>\n

\n The Signal Processing Laboratory was an interdisciplinary group focused on research in signal processing and biomedical imaging with special interest in microscopy. It was also dedicated to the training of life science researchers in image processing in order to establish a common language and a critical vision in these techniques.<\/span>\n <\/p>\n

\n The signal processing offered an objective approach that allows to automatize and systematize the analysis of data generated by the wide spectrum of techniques and equipment used in the IP Montevideo, from the quantification of microscopy images to genomic sequence data.<\/span>\n <\/p>\n

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\n An interdisciplinary approach permitted developing methodologies and algorithms that incorporate knowledge of different disciplines in all stages of research.<\/span>\n <\/p>\n

\n This was a joint group with members of the Signal Processing Department of the Faculty of Engineering (Udelar) and the Institut Pasteur of Montevideo.<\/span>\n <\/p>\n

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Members<\/h2>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ use_custom_gutter=”on” gutter_width=”2″ module_class=”dfc-integrantes” _builder_version=”4.14.6″ _module_preset=”default” width_tablet=”” width_phone=”auto” width_last_edited=”on|phone” max_width=”80%” custom_padding=”||6px|||” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_column type=”1_4″ module_class=”dfc-humano” _builder_version=”4.14.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_team_member name=”Eng Federico Lecumberry, PhD” position=”Head ” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/04\/Lecumberry-Federico.jpg” _builder_version=”4.14.6″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” link_option_url_new_window=”on” hover_enabled=”0″ global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”et_body_layout” title_text=”Lecumberry, Federico” sticky_enabled=”0″]<\/p>\n

\n Faculty of Engineering, Udelar<\/span>\n <\/p>\n

[\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_team_member name=”Eng Mart\u00edn Etchart” position=”Master’s degree student” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/04\/Etchart-Martin.jpg” _builder_version=”4.14.6″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” hover_enabled=”0″ global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”et_body_layout” title_text=”Etchart, Mart\u00edn” sticky_enabled=”0″][\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ module_class=”dfc-humano” _builder_version=”4.14.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_team_member name=”Mauricio Ramos” position=”Degree student” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/04\/Ramos-Mauricio.jpg” _builder_version=”4.14.6″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” hover_enabled=”0″ global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”et_body_layout” title_text=”Ramos, Mauricio” sticky_enabled=”0″][\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.14.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_team_member name=”Alfredo Solari” position=”Degree student” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/04\/Solari-Alfredo.jpg” _builder_version=”4.14.6″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” hover_enabled=”0″ global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”et_body_layout” title_text=”Solari, Alfredo” sticky_enabled=”0″][\/et_pb_team_member][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=”1_4,1_4,1_4,1_4″ use_custom_gutter=”on” gutter_width=”2″ module_class=”dfc-integrantes” _builder_version=”4.14.6″ _module_preset=”default” width_tablet=”” width_phone=”auto” width_last_edited=”on|phone” max_width=”80%” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_column type=”1_4″ module_class=”dfc-humano” _builder_version=”4.14.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_team_member name=”Daniel Soria” position=”Degree student” image_url=”https:\/\/pasteur.uy\/wp-content\/uploads\/2022\/02\/icono-persona.jpg” _builder_version=”4.14.6″ _module_preset=”default” header_font=”|700|||||||” body_font=”|300|||||||” position_font=”|600|||||||” position_text_color=”#005293″ position_line_height=”25px” animation_style=”fade” hover_enabled=”0″ global_colors_info=”{}” position__hover_enabled=”off|desktop” theme_builder_area=”et_body_layout” title_text=”icono-persona” sticky_enabled=”0″][\/et_pb_team_member][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][\/et_pb_column][et_pb_column type=”1_4″ module_class=”dfc-humano” _builder_version=”4.14.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][\/et_pb_column][et_pb_column type=”1_4″ _builder_version=”4.14.5″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”dfc-investigacion” _builder_version=”4.14.6″ _module_preset=”default” max_width=”80%” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_column type=”4_4″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_text _builder_version=”4.14.6″ _module_preset=”default” header_2_font=”|700|||||||” header_2_text_color=”#005293″ header_2_font_size=”35px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” header_2_font_size_tablet=”35px” header_2_font_size_phone=”29px” header_2_font_size_last_edited=”on|phone” saved_tabs=”all” global_colors_info=”{}” theme_builder_area=”et_body_layout”]<\/p>\n

Research lines<\/h2>\n

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Processing of biomedical images.<\/strong>
We work on the development and integration of algorithms and tools for the quantification and analysis of images from various sources of imaging in biomedicine: optical microscopy, fluorescence, electronics, or in-vivo imaging system. Some of our lines of research and applications are: detection and long quantification and fluorescence of primary cilia, detection of parasites and calculation of infection index, monitoring of neutrophil trajectories, quantification of fluorescence dynamics in different cell and tissue treatments, reconstruction of structures three-dimensional, among others. At the Microscopy Unit of IP Montevideo, we collaborate with researchers from various groups within the institute and with researchers from the Faculty of Medicine of the Universidad de la Rep\u00fablica.<\/p>\n

Signal processing applied to bioinformatics.<\/strong>
Analysis of genomic data and application of automatic learning methods to the analysis and visualization of the evolution of viruses or the identification of proteins with fusogenic capacity. We work in collaboration with the Bioinformatics Unit (IP Montevideo) and the Institute of Mathematics of the Faculty of Engineering (Udelar).<\/p>\n

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Courses<\/h2>\n

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    \n
  • Postgraduate course \u201cProcessing of Images for Biology and Medicine\u201d (PIMBIO). Faculty of Engineering; July 2016 and November 2017. Organizer: Signal Processing Department. Responsible: Federico Lecumberry.<\/li>\n
  • Regional and postgraduate course \u201cProcessing and Analysis of Fluorescence Microscopy Images\u201d. Institut Pasteur de Montevideo; March 2016. Organizer: Microscopy Unit (IP Montevideo).<\/li>\n
  • Tutorial \u201cBases for the Processing and Analysis of Images\u201d. Institut Pasteur de Montevideo; November 2017. Organizer: Signal Processing Laboratory.<\/li>\n<\/ul>\n

    [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”dfc-proyectos” _builder_version=”4.14.6″ _module_preset=”default” max_width=”80%” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_column type=”4_4″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_text _builder_version=”4.14.6″ _module_preset=”default” header_2_font=”|700|||||||” header_2_text_color=”#005293″ header_2_font_size=”35px” custom_margin=”||0px||false|false” custom_padding=”||0px||false|false” header_2_font_size_tablet=”35px” header_2_font_size_phone=”29px” header_2_font_size_last_edited=”on|phone” saved_tabs=”all” global_colors_info=”{}” theme_builder_area=”et_body_layout”]<\/p>\n

    Projects<\/h2>\n

    [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row module_class=”dfc-proyectos” _builder_version=”4.14.6″ _module_preset=”default” max_width=”80%” custom_margin=”0px||0px||false|false” custom_padding=”0px||0px||false|false” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_column type=”4_4″ _builder_version=”4.14.6″ _module_preset=”default” global_colors_info=”{}” theme_builder_area=”et_body_layout”][et_pb_text _builder_version=”4.14.6″ _module_preset=”default” custom_margin=”||0px||false|false” custom_padding=”0px||0px||false|false” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”et_body_layout” sticky_enabled=”0″]<\/p>\n

    2015\u20132018<\/strong> \u2013 Design of biosensors for simultaneous monitoring of redox signaling and cAMP: From the computer to the cell and back to the computer.<\/p>\n

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    Main publications<\/h2>\n

    [\/et_pb_text][et_pb_accordion icon_color=”#005293″ _builder_version=”4.14.6″ _module_preset=”default” toggle_text_color=”#005293″ toggle_font=”Titillium Web|600|||||||” toggle_font_size=”17px” custom_margin=”||||false|false” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”et_body_layout” sticky_enabled=”0″][et_pb_accordion_item title=”vacio” open=”on” _builder_version=”4.14.6″ _module_preset=”default” custom_css_main_element=”display:none” global_colors_info=”{}” theme_builder_area=”et_body_layout”][\/et_pb_accordion_item][et_pb_accordion_item title=”2018″ _builder_version=”4.14.6″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”et_body_layout” sticky_enabled=”0″]<\/p>\n

    Kinesin 1 regulates cilia length through an interaction with the Bardet-Biedl syndrome related protein CCDC28B Rossina Novas, Magdalena Cardenas-Rodriguez, Paola Lepanto, Mat\u00edas Fabregat, Magela Rodao, Maria Ines Fariello, Mauricio Ramos, Camila Davison, Gabriela Casanova, Luc\u00eda Alfaya, Federico Lecumberry, Gualberto Gonz\u00e1lez-Sapienza, Florencia Irigoin, Jos\u00e9 L. Badano Scientific Reports, Volume 8, Number 3019, page 1\u201316 \u2013 Feb. 2018<\/p>\n

    [\/et_pb_accordion_item][et_pb_accordion_item title=”2017″ _builder_version=”4.14.6″ _module_preset=”default” link_option_url_new_window=”on” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”et_body_layout” sticky_enabled=”0″]<\/p>\n

    Quantification of structural changes in the rodent somatosensory cortex. Mauricio Ramos, Javier Nogueira, Diego M\u00e9ndez, Federico Lecumberry. XIV Congreso CIASEM 2017, Varadero, Cuba, 25-29 sep \u2013 2017<\/p>\n

    [\/et_pb_accordion_item][et_pb_accordion_item title=”2016″ _builder_version=”4.14.6″ _module_preset=”default” hover_enabled=”0″ global_colors_info=”{}” theme_builder_area=”et_body_layout” sticky_enabled=”0″]<\/p>\n

    Similarity measure for cell membrane fusion proteins identification. Daniela Megrian, Pablo S. Aguilar, Federico Lecumberry. Progress in Pattern Recognition, Image Analysis, Computer Vision, and Applications : 21st Iberoamerican Congress, CIARP 2016, Lima, Per\u00fa, November 8-11, 2016, Lecture Notes in Computer Science, Springer, , page 257\u2013265 \u2013 2016.<\/p>\n

    Medida del largo de cilias primarias : Un plugin para ImageJ. Mauricio Ramos, Paola Lepanto, Florencia Irigoin, Federico Lecumberry. Acta Microsc\u00f3pica, Volume 25 Supp A \u2013 2016.<\/p>\n

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    A confocal microscopy image analysis method to measure adhesion and internalization of Pseudomonas aeruginosa multicellular structures into epithelial cells. Paola Lepanto, Federico Lecumberry, J\u00e9ssica Rossello, Arlinet Kierbel. Molecular and Cellular Probes, Volume 28, Number 1, page 1-5. Feb. 2013.<\/p>\n

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    Signal Processing The Signal Processing Laboratory was an interdisciplinary group focused on research in signal processing and biomedical imaging with special interest in microscopy. It was also dedicated to the training of life science researchers in image processing in order to establish a common language and a critical vision in these techniques. The signal processing […]<\/p>\n","protected":false},"author":8,"featured_media":5411,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[50],"tags":[],"dipi_cpt_category":[],"class_list":["post-5428","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-previous-laboratories"],"acf":[],"_links":{"self":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/posts\/5428","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/comments?post=5428"}],"version-history":[{"count":2,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/posts\/5428\/revisions"}],"predecessor-version":[{"id":5430,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/posts\/5428\/revisions\/5430"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/media\/5411"}],"wp:attachment":[{"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/media?parent=5428"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/categories?post=5428"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/tags?post=5428"},{"taxonomy":"dipi_cpt_category","embeddable":true,"href":"https:\/\/pasteur.uy\/en\/wp-json\/wp\/v2\/dipi_cpt_category?post=5428"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}