María Eugenia Francia

María Eugenia Francia, PhD

Laboratorio de
Biología de Apicomplejos

  • PhD en Biología Celular (Énfasis en Parasitología Molecular). 07/2013. University of Georgia. Athens, GA. USA. (2009-2013).
  • MSc en Biología Molecular, Microbiología y Bioquímica. University of Idaho, Moscow, ID. USA. (2008-2009).
  • Licenciatura en Biología Molecular y Bioquímica (B.Sc.). University of Idaho, Moscow, ID. USA. (2004-2007).
  • Apicomplejos
  • División Celular
  • Salud Animal
  • Biología Molecular
  • Transmisión Vertical
  • Manipulación genética
  • Biología Celular
  • Diagnóstico
  • Cabrera A, Berná L, Fresia P, Silveira C, Macias Rioseco M, Pritsch O, Riet-Correa F, Giannitti F, Francia ME*, Robello C*. (2019). Characterization of Four Novel Neospora Caninum Strains Reveals Underappreciated Regional and Worldwide diversity. Submitted. *co-corresponding author.
  • Berry, L., Chen, CT, Francia, M.E. et al. (2018). Toxoplasma gondii chromosomal passenger complex is essential for the organization of a functional mitotic spindle: a prerequisite for productive endodyogeny. Cell. Mol. Life Sci.
  • Marteil G, Guerrero A, Vieira A, Machado P, Mendonça S, Mesquita M, Villarreal B, Fonseca I, Francia ME, Dores K, Tranfield E, Paredes J, Pellman D, Godinho S, Bettencourt-Dias M. (2018). Over-elongation of centrioles in cancer promotes centriole amplification and chromosome missegregation. Nature Comm.
  • Zitouni S*,#, Francia ME*,#, Leal F, Montenegro-Gouveia S, Nabais C, Duarte P, Gilberto S, Brito D, Kandels-Lewis S, Ohta M, Kitagawa D, Holland AJ, Karsenti E, Lorca T, Lince-Faria M, Bettencourt-Dias M# (2016). CDK1/Cyclin B prevents unscheduled PLK4-STIL complex assembly restricting centriole biogenesis to one round per cell cycle. Curr Biol. 2016 Apr 20. pii: S0960-9822(16)30300-1. *First co-author #corresponding author.
  • Francia ME#, Dubremetz JF, Morrissette NS. (2016) Basal Body Structure and Composition in the Apicomplexans Toxoplasma and Plasmodium. Review series on Basal Bodies across Eukaryotes. Cilia. Feb 4; 5:3. #corresponding author.
  • Lopes CAM, Chandra Jana S, Cunha-Ferreira I, Zitouni S, Bento I, Duarte P, Gilberto S, Freixo F, Guerrero A, Francia M, Lince-Faria M, Carneiro J, Bettencourt-Dias M. (2015) PLK4 trans-autoactivation regulates centriole biogenesis in space. Dev. Cell. Oct 26; 35 (2): 222-35.
  • Suvorova E, Francia ME, Striepen B and White M. (2015). A Unique Bipartite Centrosome Coordinates the Apicomplexan Cell Cycle. PLoS Biol. 13(3): e1002093.
  • Lentini G, Kong-Hap M, El Hajj H, Francia M, Berry L, Claudet C, Striepen B, Dubremetz J-F, Lebrun M. (2015). Identification and characterization of Toxoplasma Nemo, a conserved cytoskeleton protein involved in maintaining the structure of the inner membrane complex. Cell Microbiol. Jan; 17(1):62-78.
  • Francia ME and Striepen B. (2014). Cell Division in Apicomplexan Parasites. Nat Rev Microbiol. Jan 2; 12(1) (by invitation).
  • Francia ME, Jordan CN, Patel JD, Sheiner L, Demerly JL, et al. (2012). Cell Division in Apicomplexan Parasites Is Organized by a Homolog of the Striated Rootlet Fiber of Algal Flagella. PLoS Biol. 10(12): e1001444.
  • Francia ME, Wicher S, Pace D, Sullivan J, Moreno S, Arrizabalaga G. (2011). A Toxoplasma gondii protein with homology to intracellular type Na+/H+ Exchangers is important for osmoregulation and invasion. Exp Cell Res. Jun 10; 317(10):1382-96.
  • Brooks CF, Francia ME, Gissot M, Croken MM, Kim K, Striepen B. (2011) Toxoplasma gondii sequesters centromeres to a specific nuclear region throughout the cell cycle. Proc Natl Acad Sci (PNAS). Mar 1;108(9):3767-72. Epub 2011 Feb 14.
  • Harrington JM, Widener J, Stephens N, Johnson T, Francia M, Capewell P, Macleod A, Hajduk SL. (2010) The plasma membrane of bloodstream-form African trypanosomes confers susceptibility and specificity to killing by hydrophobic peptides. J Biol Chem. Sep 10;285 (37):28659-66. Epub 2010.