Hugo Naya 2018-12-12T23:18:42+00:00
PhD Hugo Naya
PhD Hugo Naya

Bioinformatic

  • PhD, University of Wisconsin, Madison, Estados Unidos (2005).

  • PhD in Biological Science, Faculty of Science (Udelar), PEDECIBA, Uruguay (2000 – 2004).

  • BSc in Biological Science, Faculty of Science, Universidad de la República, Uruguay (1995-1999).

  • Medical Genetics

  • Rare diseases

  • Mitochondrial pathologies

  • Genomics

  • Quantitative and statistical genetics

  • Human genome

  • Genetic anthropology

  • Mitochondrial DNA

  • Iraola G, Forster SC, Kumar N, Lehours P, Bekal S, García-Peña FJ, Paolicchi F, Morsella C, Hotzel H, Hsueh PR, Vidal A, Lévesque S, Yamazaki W, Balzan C, Vargas A, Piccirillo A, Chaban B, Hill JE, Betancor L, Collado L, Truyers I, Midwinter AC, Dagi HT, Mégraud F, Calleros L, Pérez R, Naya H, Lawley TD (2017) “Distinct Campylobacter fetus lineages adapted as livestock pathogens and human pathobionts in the intestinal microbiota” Nature Communications DOI: 10.1038/s41467-017-01449-9.

  • Spangenberg L, Graña M, Greif G, Suárez Rivero JM, Krysztal K, Tapié A, Boidi M, Fraga V, Lemes A, Gueçaimburú R, Cerisola A, Sánchez Alcázar JA, Robello C, Raggio V, Naya H (2016). “3697G>A in MT-ND1 is a causative mutation in mitochondrial diseases”. Mitochondrion 28:54-9. doi: 10.1016/j.mito.2016.03.006.

  • Iraola G, Spangenberg L, Lopes-Bastos B, Graña M, Vasconcelos L, Almeida A, Greif G, Robello C, Ristow P, Naya H (2016). “Transcriptome sequencing reveals wide expression reprogramming of basal and unknown genes in Leptospira biflexa biofilms”. mSphere 10.1128/mSphere.00042-16.

  • Naya DE, Spangenberg L, Naya H, Bozinovic F (2012) “How does evolutionary variation in basal metabolic rates arise? A statistical assessment and a mechanistic model”. Evolution 67(5):1463-76.

  • Iraola G, Vazquez G, Spangenberg L, Naya H. (2012) “Reduced set of virulence genes allows high accuracy prediction of bacterial pathogenicity in humans”. PLoS ONE 7(8):e42144.

  • de Los Campos G, Naya H, Gianola D, Crossa J, Legarra A, Manfredi E, Weigel K, Cotes JM. (2009). “Predicting Quantitative Traits with Regression Models for Dense Molecular Markers and Pedigrees”. Genetics 182(1):375-85.

  • Naya H, Urioste JI, Chang YM, Rodrigues-Motta M, Kremer R, Gianola D. (2008). “A comparison between Poisson and Zero-inflated Poisson regression models with an application to number of black spots in Corriedale sheep”. Gen Sel Evol 40:379-394.

  • Marton S, Garcia MR, Robello C, Persson H, Trajtenberg F, Pritsch O, Rovira C, Naya H, Dighiero H, Cayota A. (2008). “Small RNAs analysis in CLL reveals a deregulation of miRNA expression and novel miRNA candidates of putative relevance in CLL pathogenesis”. Leukemia 22:330-8.

  • Naya H, Gianola D, Romero H, Urioste JI, Musto H. (2006). “Inferring parameters shaping amino-acid usage in prokaryotic genomes via Bayesian MCMC methods”. Mol Biol Evol 23:203-11.

  • Naya H, Romero H, Zavala A, Alvarez B, Musto H. (2002). “Aerobiosis Increase Genomic GC% in Prokaryotes ”. J Mol Evol 55(3): 260-4.