Andrés Abin

PHC Andrés Abin, PhD

Biopharmaceutical Laboratory

  • PhD in Chmistry, Chemistry Faculty, Pedeciba, Udelar (2004-2010).
  • Pharmaceutical chemist, Chemistry Faculty, Udelar (1993-2001).
  • Bioanalytical methods
  • Biopharmaceutical
  • Quality Control
  • Biotechnology
  • Purification, structural elucidation, antioxidant capacity and neuroprotective potential of the main polyphenolic compounds contained in Achyrocline satureioides (Lam) D.C. (Compositae). Martínez-Busi M, Arredondo F, González D, Echeverry C, Vega-Teijido MA, Carvalho D, Rodríguez-Haralambides A, Rivera F, Dajas F, Abin-Carriquiry JA. Bioorg Med Chem. 2019 Jun 15;27(12):2579-2591.
  • Alterations in the Gut Microbiota of Rats Chronically Exposed to Volatilized Cocaine and Its Active Adulterants Caffeine and Phenacetin. Scorza C, Piccini C, Martínez Busi M, Abin Carriquiry JA, Zunino P. Neurotox Res. 2019 Jan;35(1):111-121.
  • Identification and Quantification of Cocaine and Active Adulterants in Coca-Paste Seized Samples: Useful Scientific Support to Health Care. Abin-Carriquiry JA, Martínez-Busi M, Galvalisi M, Minteguiaga M, Prieto JP, Scorza MC. Neurotox Res. 2018 Aug;34(2):295-304.
  • Structural evidence of quercetin multi-target bioactivity: A reverse virtual screening strategy. Carvalho D, Paulino M, Polticelli F, Arredondo F, Williams RJ, Abin-Carriquiry JA. Eur J Pharm Sci. 2017 Aug 30;106:393-403
  • After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult. Arredondo F, Echeverry C, Abin-Carriquiry JA, Blasina F, Antúnez K, Jones DP, Go YM, Liang YL, Dajas F. Free Radic Biol Med. 2010 Sep 1;49(5):738-47.
  • In silico characterization of cytisinoids docked into an acetylcholine binding protein. Abin-Carriquiry JA, Zunini MP, Cassels BK, Wonnacott S, Dajas F. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3683-7.
  • Nicotine prevents striatal dopamine loss produced by 6-hydroxydopamine lesion in the substantia nigra. Costa G, Abin-Carriquiry JA, Dajas F. Brain Res. 2001 Jan 12;888(2):336-342.