The Advanced Bioimaging Unit (Joint Unit Pasteur + Hospital de Clínicas / Udelar) is calling for applicants to carry out their PhD thesis with an hourly load of 30 hours per week.
Training attained
We are looking for interested people who are able to enroll in a PhD program and are interested in doing their thesis in the field of Biomedicine/Biotechnology. It is a requirement to have completed a Master’s degree, or accredit equivalent training, in Biological Sciences, Biochemistry, Human Biology, Biotechnology, Medicine, Veterinary Medicine, or related areas. Special cases may be considered of people who are not yet able to enter the Doctorate, but are able to enter a Master’s program (for guidance, please refer to the requirements of the PEDECIBA or PROINBIO doctorate).
Experience
Knowledge and interest in neurosciences, biochemistry, cellular-developmental biology, biotechnology, microscopy, as well as experience in some of the methodological techniques to be applied during the project and described in this call will be valued, but not exclusive.
Responsibilities
The PhD thesis will be carried out in the framework of the ANII-funded project: “SCiMeR: an innovative platform for in vivo and single cell level preclinical evaluation of molecules modulating metabolic reprogramming” (FMV 1_2023_1_176623). The project aims to develop new methods for in vivo analysis of cell behavior and physiology, focusing on metabolic changes in immune and microglial cells.
The selected person will have the opportunity to:
● research using advanced microscopy technology unique in the country and the region, with the direct objective of applying the knowledge acquired to the preclinical evaluation of drugs.
● be part of a dynamic, interdisciplinary and collaborative working group, with extensive experience in the subject matter of work.
● given the applied nature of the project, you will have contact with companies, all of which will provide an enriching training experience in multiple areas.
Some of the main techniques to be used during the project will be:
● Cell and tissue cultivation.
● Basic molecular biology and biochemistry techniques.
● Use and manipulation of laboratory animals, mainly zebrafish embryos.
● Advanced Fluorescence Optical Microscopy techniques including: Immunolocalization and 3D reconstruction, in vivo imaging with microscopy.
2-photon confocal laser, Fluorescence Lifetime Imaging (FLIM), hyperspectral microscopy and Light-sheet Microscopy.
● Image analysis and statistical data processing.
Remuneration
The selected person will receive support for the completion of the doctorate through an ANII postgraduate scholarship associated with the project.
Duration
The project will start on May 1, 2024 and the ANII project financing will have a duration of 36 months.
The selected person will develop his/her activities in the Joint Udelar- Institut Pasteur Unit of Advanced Bioimaging (based at the Hospital de Clínicas and the Institut Pasteur de Montevideo) and will eventually carry out stay(s) in centers abroad.
We invite interested people to apply through this link attaching in pdf format, the following documents:
a) Motivation letter explaining current situation and academic interests (maximum 1 page).
b) CV.
c) ) Name and contact of 2 persons to provide references.
The deadline for receipt of applications is February 18, 2024.
If you have any questions about the call, please send an e-mail to llamados@pasteur.edu.uy.
The Institut Pasteur de Montevideo is an institution committed to promoting an organizational culture based on gender equality. The Institution adheres to Law Nº 17.817 on the fight against racism, xenophobia, and all other forms of discrimination, and Law No. 18.104 on equal rights and opportunities between men and women.